How to choose a vitamin D supplement

A large segment of the population would benefit from supplementing with vitamin D in winter. But in what form and at what dose should you take the “sunshine vitamin”? With the advice of Dr. Brigitte Houssin, doctor and author of Vitamin D – instructions for use.

Why supplement with vitamin D

Vitamin D is involved not only in bone health but also in many other functions of the body, including immunity. There

  • References

  • Historical

  1. Holick. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr. 2004.

  2. Zittermann et al. Vitamin D and Cardiovascular Disease: An Updated Narrative Review. Int J Mol Sci. 2021.

  3. Mondul et al. Vitamin D and Cancer Risk and Mortality: State of the Science, Gaps, and Challenges. Epidemiol Rev. 2017.

  4. Anglin et al. Vitamin D deficiency and depression in adults: systematic review and meta-analysis. Br J Psychiatry. 2013.

  5. Martens et al. Vitamin D’s Effect on Immune Function. Nutrients. 2020.

  6. Charoenngam and Holick. Immunologic Effects of Vitamin D on Human Health and Disease. Nutrients. 2020.

  7. Public Health France. Health study on environment, biomonitoring, physical activity and nutrition (Esteban) 2014—2016. Nutrition aspect. Chapter Biological dosages: vitamins and minerals. December 2019.

  8. Haines and Park. Vitamin D supplementation: what’s known, what to do, and what’s needed. Pharmacotherapy. 2012.

  9. Wang et al. Optimal methods of vitamin D supplementation to prevent acute respiratory infections: a systematic review, dose–response and pairwise meta-analysis of randomized controlled trials. Nutr J. 2024.

  10. Yang et al. Vitamin D Supplementation Improves Cognitive Function Through Reducing Oxidative Stress Regulated by Telomere Length in Older Adults with Mild Cognitive Impairment: A 12-Month Randomized Controlled Trial. J Alzheimers Dis. 2020.

  11. Ekwaru et al. The importance of body weight for the dose response relationship of oral vitamin d supplementation and serum 25-hydroxyvitamin d in healthy volunteers. PLoS One. 2014.

  12. French Pediatric Society. Vitamin D. Site sfpediatrie.com.

  13. Zhuang et al. Efficacy of intermittent versus daily vitamin D supplementation on improving circulating 25(OH)D concentration: a Bayesian network meta-analysis of randomized controlled trials. Dry. Nutritional Epidemiology. 2023.

  14. Grossmann and Tangpricha. Evaluation of vehicle substances on vitamin D bioavailability: A systematic review. Mol Nutr Food Res. 2010.

  • Current version

    09/10/2025

    Updated by Marie-Céline Ray


    Science journalist

  • on 06/17/2025

    Updated by Marie-Céline Ray

  • on 02/06/2025

    Updated by Marie-Céline Ray

  • on 01/13/2025

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